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Alexandra Jacunski is a first-year graduate student at Columbia University in the Integrated Program in Cellular, Molecular, and Biomedical Studies. She hopes to focus on some combination of microbiology, pharmacology, and computational biology. Undergraduate degree completed at Columbia College of Columbia University (B.A. Biology and English Literature, 2011)

Thursday, January 3, 2013

So This Is the New Year

2012 was a ridiculous year. So many things happened, the most notable being that I was interviewed and accepted for my top-choice PhD program. I began in September, and what a whirlwind it's been. Me being me, I took on far too much, and went a little crazy first semester - but it's been a wonderful journey so far, and I'm excited for what 2013 will bring.

I've made some amazing friends, and refound old ones, including a best friend with whom I'd had a falling out in sophomore year of college. I've been truly blessed to have such a supportive network of friends and family, although I get terribly homesick sometimes.

I've also discovered a lot about myself -- including that I'm a lot stronger than I thought I was, and that I have a capacity for happiness infinitely larger than I thought it could be. Even in the darkest days, when experiments were going wrong and programs just weren't running like I wanted them to, I could lie down at the end of the day and think that I'm exactly where I want to be. It's a great feeling.

As ever, though, there are things I want to change, to improve about myself. And so, with this, I bring you my list of New Year's Resolutions. I know, I know -- this is a revolutionary concept, the first blog post of its kind. Please bear with me.

1. Stop being scared of failure. This has been one of my biggest shortcomings. A key example: I had to do a final presentation for my lab. I was very nervous for it, and so kept putting off putting together, telling myself that I was just thinking and planning. I ended up getting it all together the night before, and of course it fell short of how good I wanted it to be. So: whatever I'm most nervous to start, I will start first -- I will sound my barbaric yawp over the rooftops of this world, and conquer whatever the task may be, because damnit Jim, I'm a PhD student, not a coward.

To help myself accomplish this, I'm first being much more aware of overloading myself with activities, and second, I will prioritize projects due on my monthly calendar hanging in my bedroom by colour. Red will mean SCARY, like a presentation (gleeps!). Orange will mean less so. Green will mean regular things, like homework.

2. Exercise. I showed myself this year that, holy moly, I can actually be athletic. I started lifting, I started running; I did a 10k obstacle race, and a zombie run. I also stopped running and lifting regularly when I got to school because I had so much on my plate. Since I'm signed up for a half-marathon, two Tough Mudders, and at least three other races in 2013... I can't really let myself drop the ball.

To help myself do this, I've signed up for Fitocracy, because I really liked the RPG aspects of Nerd Fitness. I'm also putting a little less on my plate, so I will hopefully have more time for working out. Finally, I'm going to start writing on my wall calendar when I've worked out, so I can see what progress I've been making with keeping up the regularity.

3. Cook more regularly, and more healthily. I did really well with this at the start of last semester, but died around midterms and basically just made nachos for every meal thereafter. Oh gosh I love nachos, and I can already feel myself wanting to make them. I also need to stop wasting food, because there have been too many times when I've bought something and then thrown it out before using it (shame on me).

To help myself do this: I want to bring lunch to work every day (unless I know I'll have a free lunch that day), so I will order my groceries on weekends, and prepare as much as I can (e.g. trimming green beans so I only need to cook them, etc) on Sundays. I'm also going to start tracking my meals and go over them every weekend to see how well I did with eating decently. A side project will be to try a new recipe every month, but we'll see how that pans out.

4. Do a NYTimes Crossword Every Day. Maybe not the whole thing on later days, but take 20 minutes to do (part of) one daily. I think it keeps my mind working well, and they're nice to do as I lie in bed, even if I only got home at 4am from the library.

5. Read every day. I'm getting excerpts of Les Miserables delivered to my inbox daily; each takes me about 15 minutes to read. I can do this over lunch. :) Even a chapter will be good!

6. Take more time for self-reflection. I want to think about what I've done well each week, and what I've failed at. It's too easy to get lost in one's mistakes, and I think I've gotten better at moving on from them; that being said, I also want to address them and try to make myself better. How did I disappoint myself? Why? What did I do this week that I'd done poorly before? I'm finally okay with the person that I'm seeing in the mirror. Now I want to work on being proud of that person.

7. Be more lady-like. Less swearing. Less whoops-I-got-too-drunk. If you have more suggestions, I welcome them.

8. Revive this blog. One post a week about anything at all. I can do that. I will post on Saturday mornings.

9. BUDGET. Oh gosh I'm terrible at this. Month-to-month, I can do it, but for first year of grad school, we get our stipends in bulk for a few months at a time. It... could have gone more smoothly. So. Less Starbucksing; less eating out (social is fun; lunch at work is not); less dollar-here-dollar-there spending, because that adds up too fast. Anything I want to buy online, I put in my shopping cart, then come back to the next day.

At this point, I said out loud, "Do I want any more resolutions?" My mother responded, "To quit smoking." We are both aware that I do not smoke. Helpful, mom.

I think that's all. :) Although I'd be happy to find a 10th, because I like 'round' numbers.

Friday, March 30, 2012

"Last Hoorah" Reading List

This is what I'll look like, except with my current
Lucius Malfoy hair.
This summer, I want to get in a good "last hoorah" binge. I'm not talking a two-books-a-week kind of reading schedule that I tend to define a binge, between school and work obligations. Oh no.

I'm talking, 100 books in 3 months.* That kind of binge.  I'm going to try to avoid War-and-Peace/Infinite-Jest-length books, because even though I read fast, I'm not a superhero. I may add to that number with a few Shakespeare plays, too, just to refresh.

Why am I writing about this here?

Well... I want your help. I have 48 books I want to get through, in no particular order, all recommended by the same person. I want your knowledge to help me add to that list: the books that you loved, the books that changed you, the books you still ache about having to have finished. The books with the characters you just can't forget or let go of. Comment below with your suggestions! Once I get 100+ books suggested, I'll prune the list and come up with a final version I'll post here (this list may or may not include my original 48). I'll try to blog regularly about my adventure (thereby veering away from the science theme of this blog) - you're welcome to follow me or read along!

As a guide: I can get through approximately 300 pages of not-too-heavy writing in a day quite easily. I hated Grass' The Flounder, Twilight, and anything by Bukowski. Leonard Cohen inspires me. I'm still looking for my "Lit Crush." I love books about science. I didn't like The Pillars of the Earth. I'll be happy to pick up any fiction book, as long as it inspired you in some way.

My List So Far, in No Particular Order...

  • Toni Morrison - Song of Solomon
  • Ralph Ellison - Invisible Man
  • JM Coetzee - Age of Iron
  • Gabriel Garcia Marquez - Love in the Time of Cholera
  • Philip Roth - American Pastoral
  • Chinua Achebe - Things Fall Apart
  • Darkness at Noon - Arthur Koestler
  • John Updike - Rabbit, Run
  • James Baldwin - Go Tell it on the Mountain
  • Don DeLillo - White Noise
  • EL Doctorow - Ragtime
  • Walker Percy - The Moviegoer
  • John Kennedy Toole - A Confederacy of Dunces
  • Tim O'Brien - The Things They Carried
  • Ford Maddox Ford - The Good Soldier
  • Malcom Lowry - Under the Volcano
  • Colm Toibin - The Blackwater Lightship
  • Jack Kerouac - On The Road
  • Katherine Dunn - Geek Love
  • Raymond Carver - What We Talk About When We Talk About Love
  • Katherine Ann Porter - Ship of Fools
  • Graham Greene - The Power and the Glory
  • Norman Mailer - The Naked and the Dead
  • William Kennedy - Ironweed
  • John Fowles - The French Lieutenant's Woman
  • Carson McCullers - The Heart is a Lonely Hunter
  • Alice Walker - The Colour Purple
  • Richard Wright - Native Son
  • Zadie Smith - White Teeth
  • Denis Johnson - Tree of Smoke
  • Colson Whitehead - The Intuitionist
  • Michael Chabon - The Adventurs of Kavalier and Clay
  • John Banville - The Sea
  • Dave Eggers - What is What
  • David Leavitt - The Indian Clerk
  • Jonathan Lethem - Fortress of Solitude
  • Gao Xinglian - Soul Mountain
  • Ivo Andric - The Bridge on the Drina
  • VS Naipaul - A House for Mr Biswas
  • Christina Garcia - Dreaming in Cuban
  • M Scott Mamaday - House Made of Dawn
  • Alan Paton - Cry, the Beloved Country
  • Julia Alvarez - In the Time of the Butterflies
  • Louise Erdrich - Love Medicine
  • Tom Robbins - Skinny Legs and All
  • Isaac Asmiov - Foundation
  • Orson Scott Card - Ender's Game



*Whatever I don't finish in that three-month summer period, I intend to finish before the start of 2013. Yes, I'm setting the goal crazy-high, because I'm masochistic like that - it'll help me push forward. I'll have a back-up list of up to 50 books (if I get that many suggestions) as well. What can I say - I like checklists.

Friday, March 9, 2012

Book Review: The Poisoner's Handbook

The Poisoner's Handbook by Deborah Blum

Did you know... that the US government tried to stop people from drinking bootleg alcohol during Prohibition by adding extra poisons to methanol?

Details: I bought this book months ago, inspired by a BookRiot.com post. I figured it would be an interesting read, as it encompasses many things I find fascinating: science, history, and murder. I was not disappointed - the book was everything I had hoped for and more.

Blum traces the history of forensic toxicology using poisons as 'markers' - each chapter is wound around a specific theme, such as carbon monoxide or methanol. These smaller sections are all linked together with several stories: the rise and fall of Prohibition in the United States; the creation of the first position of Chief Medical Examiner in NYC; and many murder cases. She also illustrates - briefly yet effectively - how necessary a body like the FDA was and continues to be.

The Nerdiness Continues

Stop by BookRiot.com to check out my most recent contribution, part of their Genre Kryptonite series.

New posts coming soon!

Thursday, March 1, 2012

Book Review: Microbe Hunters

Yes, I'm back! Sorry for disappearing for so long - a few really big events happened. The most exciting: well... I can't tell you until May/Juneish. But it's exciting, I promise! The least happy: my boyfriend of two years asked for a break, so I'm floating in kind-of-sort-of single land right now. Since we're not talking, however, I've got a lot of free time to focus on my writing, which will hopefully mean I'll have lots of nifty articles for you guys. Anyway, without further ado...


The Microbe Hunters by Paul de Kruif
Originally published in 1926

I picked up this book as a reward to myself for... well, something. :) I vaguely recalled somebody (likely my former Virology prof) mentioning it in one of my classes as an interesting book; so, upon seeing it on a shelf in B&N, I decided to grab it for the overnight bus trip back to New York. I was already halfway through The Sisters Brothers, an amusing novel, but I wanted a book with scientific substance to it.

For anyone with the slightest interest in microbiology, or the processes of scientific discovery: do what I did and read it.

de Kruif has a very nonchalant style; as he tells the stories of several of the most important microbiologists and their most famous discoveries, I imagine him sitting in front of me, excitedly chattering away, rather than feeling I'm actually reading a book. Though he clearly takes liberties with inner dialogue of the scientists and their conversations with those around them, these help to add to the story-telling nature of his narration.

Pasteur, via Wikipedia
Microbe Hunters comprises twelve stories, describing the work of Leeuwenhoek (inventor of the microscope), Pasteur (who helped make French beer better with his knowledge of microbiology, among many other things), and Smith (who discovered that animals can act as vectors to transmit disease). One of the best things about the book, however, is that it goes not only into the scientific details of the discoveries; rather, it also follows the personal development and characteristics of the scientists as well. In spite of the fact that I've been surrounded almost solely by scientists for the past year, it still amazes me that all of the men de Kruif speaks of were so vastly different.


This book is a great read for non-scientists looking for a good chunk of history and a better understanding of the scientific process - like I mentioned before, it reads more like a story than a non-fiction book. Because he chronicles microbiology from the first time microbes were seen to the beginnings of treatment, you learn along with the scientists as they were trying to separate truth from fiction. It's not riddled with technical jargon that will confuse you and put you to sleep.

ThinkGeek.com's interpretation of rabies, in plush form.
For scientists (especially starting ones), I think this is a great book to read to also understand the scientific process and what is required to succeed. Perhaps the most frustrating thing about this book was the realization that most of science (as Ehrlich himself pointed out) is pure dumb luck - regardless of how hard you may work, you just have to get lucky to make that big break. Of course, the harder you work, the luckier you'll tend to be - so, I suppose, this entire work is both a warning to those new to science, and a call to arms as well: work your butt off, and you'll reap the rewards.

As someone who wants to eventually work in microbiology, I really enjoyed the survey nature of Microbe Hunters: I feel like I understand the foundations upon which the field is built much better, which makes me very happy indeed.

I have one caveat for this book: because it was written in 1926, it's got a nice smattering of racism in it. If you are sensitive to this kind of language, or if you will be reading this with a child, please keep this in mind.

Happy reading!

Saturday, January 7, 2012

On Being Absent

In case you all haven't noticed from my lack of posting for almost (over?) a month, life has caught up with me. I've got a lot of lab, personal, and class stuff all going on at once and I likely won't be back posting regularly until February. Alas! Check back once in a while just in case I feel particularly inspired to post something, just in case :]

-O

Sunday, December 4, 2011

Taking Advantage of Viruses


Image of Flu Virus via Wikipedia
Did You Know... that we can take advantage of the high mutation rate of viruses?

The Details: I'm sure that all of you, at one point or another, have had a vaccine at some point. The basic idea of a vaccine is that it lets your immune system "see" a pathogen in a harmless way so that, if you encounter that pathogen again, your body will remember it and attack it again. If our bodies encounter a pathogen that they have never seen before, they just don't know what to do - not for a bit, at least. Remember the flu pandemic of 1918?